Three-tier stratification for CNS COVID-19 to help decide which patients should undergo lumbar puncture with CSF analysis: a case report and literature review

Abstract The COVID-19 pandemic continues to overwhelm global healthcare systems. While the disease primarily causes pulmonary complications, reports of central nervous system (CNS) involvement have recently emerged ranging from encephalopathy stroke. This raises a practical dilemma for clinicians as when pursue neuroimaging and lumbar tap with cerebrospinal fluid (CSF) analysis in patients neurological symptoms. We present case an encephalopathic patient infected SARS-CoV-2 no propose three-tier risk stratification CNS aiming help decide which should undergo CSF analysis. examination remains integral component screening evaluating considering range emerging complications.